Studies upon leprosy. V. A report upon the treatment of six cases of leprosy with nasteine (Deycke) / by Walter R. Brinckerhoff and James T. Wayson. VI. Leprosy in the United States of America in 1909 / by Walter R. Brinckerhoff.

  • Brinckerhoff, Walter Remson, 1874-1911.
Date:
1909
Catalogue details

Licence: In copyright

Credit: Studies upon leprosy. V. A report upon the treatment of six cases of leprosy with nasteine (Deycke) / by Walter R. Brinckerhoff and James T. Wayson. VI. Leprosy in the United States of America in 1909 / by Walter R. Brinckerhoff. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    General condition at beginning of treatment.—Irregular nodular enlargement of both ears, most marked on the left side. Some infiltration of both cheeks and of forehead; accessible nerve trunks not enlarged or nodular. Trunks and limbs not notable. General infection with scabies. Diagnosis of leprosy confirmed by bacterial examination of tissue excised from left ear. General condition after nine months’ treatment.—Right ear shows extensive nodular formation, particularly around the rim. Left ear shows no nodules along the rim, but the lobule is swollen. Face shows massive infiltration of right cheek and of brow. Infiltration, but less extensive, on left cheek. Infiltrated area is indurated and dusky red, with slight superficial irregularities. Skin is shiny; eye- brows absent; trunk negative. Forearm and hands dusky red, with some furfuracious scaling. Several nodules on left wrist, extensor surface, which are from 0.5 to 2 cm. in extent and elevated 0.5 cm. Skin surface over the nodules is similar to that over the infiltration on the face. Both hands show marked drumstick fingers. Pink and brown macules from 4 to 9 mm. in extent over buttocks and posterior aspect of thighs. Legs and feet show dusky red skin, with fine cracks and slight sliininess. General condition after fifteen months and one week of treatment.— Both ears show extensive infiltration and nodule formation along rim of helix; both ears now equally involved. Infiltration of cheeks somewhat increased since last examination. Right forearm: Nodules increased in size; infiltration of the dorsal aspect of the little and third fingers of the right hand; left hand shows no infiltration. Five nodules on extensor aspect of the left forearm, ranging from one-half to 1 cm. in extent. Generalized scabies infection. Ulceration on the mucous membrane of the cartilaginous septum of the nose on the left side, with atrophy of the cartilage. Aside from scabies the trunk is negative. Macule formation as before. Legs and feet as before. Summary of case 1.—A case of tubercular leprosy in a part Hawaiian boy of 10 years of age during fifteen months of treatment with nastine showed no amelioration of the disease, but rather a steady increase in the severity and-extent of the lesions. No constitutional reaction was observed at any time during the treatment. Case 2. (K. 2.) A part Hawaiian; age, 20 years; male. Duration, four years. Type of disease, tubercular. Treatment.—One ampulla of nastine once a week from April 21 to June 5, 1908. One ampulla of nastine B. 1 twice a week from June 10 to June 29, 1908. One ampulla of nastine B. 1 three times a week from July 3 to August 31, 1908. One and one-half ampulla of nastine B. 1 three times a week from September 2 to December 6, 1908.