Notebook 1

Dr. Wyatt's notebook written during his time at the Molteno Institute, Cambridge, England. The book contains written experimental details of various biochemical laboratory techniques such as preparative electrophoresis and Dische tests. It predominantly contains the descriptions and results of Dr. Wyatt's experiments to prepare and analyse various nucleic acid samples. Results are shown from tests on nucleic acids from the virus LdV and the insect Locusta migratoria. This notebook contains Dr. Wyatt's first calculation of the molar ratios of the bases adenine, guanine, cytosine and thymine in DNA, giving evidence for the base pairing of AT and GC bases (25th October 1949).

31 January 1949 - 26 October 1949

1 notebook 1 bound notebook with three loose sheets of graph paper inserted in the back and one recently inserted page marker at a point of interest.

Experiments are recorded in chronological order from front to back with additional notes and procedures in the back pages.

A digitised copy is held by Wellcome Collection as part of Codebreakers: Makers of Modern Genetics.