Acute edema of the uvula, palate, pharynx and epiglottis, following the excessive application of adrenal solution preserved with chloretone / by Solomon Solis Cohen.

  • Solis-Cohen, Solomon, 1857-1948.
Date:
1901
Catalogue details

Licence: In copyright

Credit: Acute edema of the uvula, palate, pharynx and epiglottis, following the excessive application of adrenal solution preserved with chloretone / by Solomon Solis Cohen. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

    3/4 (page 3)
    •daily; which he did with good results. When Messrs. Parke, Davis & Company placed upon the market their solution of suprarenal substance preserved with chloretone, this was substituted for the glycerin extract formerly used. One night I was called in haste, being told that Father X. had a very severe attack of asthma and could scarcely get his breath. The appearance of the patient was different from that presented in or- dinary attacks. The face was very much flushed, but dusky; the breathing was evidently painful, and there were slight inspiratory stridor; asth- matic rales were not evident, though the stridor made in the larynx was heard over the chest. Upon examination the uvula was seen to be swollen to about three times its ordinary size, evidently much distended with fluid. In color it was nearly white. The palate and half arches and a portion of the posterior wall of the pharynx were likewise markedly edematous, and there was slight edema of the epiglottis. The interior of the larynx, fortunately was clear. The patient stated that he had gone through a period of very great use of the voice, that his throat had begun to feel uncomfortable, that he had sprayed the pharynx and nasopharynx very vigorously and for a prolonged period, possibly three or five minutes, with the suprarenal-chloretone solution. No ■effect upon the heart seemed to have been caused by the application. The uvula and palate were scarified in several places, but little fluid exuded, and scarcely a drop of blood. It was not deemed necessary to scarify the epiglottis. The patient was advised to keep at rest, a drastic purge was given, and gargling with lukewarm water, aro- matized with toilet vinegar, was advised. In about an hour, whether spontaneously or other- wise, the edema began 1o subside sufficiently to permit of greater ease in breathing; if, indeed,