Studies on the chemistry of serous effusions / by Albert A. Epstein.

  • Epstein, Albert Arthur, 1880-1965.
Date:
[1914]
Catalogue details

Licence: In copyright

Credit: Studies on the chemistry of serous effusions / by Albert A. Epstein. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    The analyses of the effusions were carried out along lines similar to those followed in the study of the blood sera.3 The substances determined were the proteins, chlorides, and incoagulable and non- protein nitrogen. Ash and total solids were also estimated in sev- eral of the fluids. A number of the fluids which were opalescent and of a chyliform appearance were analyzed for fats and other ether-soluble substances. These, however, will not be reported in the present study. The fluids subjected to analysis may be grouped according to the following scheme which is based on clinical data. 1. Cutaneous effusions: (a) nephritic and (b) cardionephritic. 2. Pleural effusions: (a) inflammatory and (b) non-inflamma- tory including (i) nephritic, (2) cardiac, (3) cardionephritic, and (4) new growth. 3. Abdominal effusions : (a) inflammatory, tuberculous, and (b) non-inflammatory, including (1) new growth, (2) cirrhosis of the liver, (3) cardiac, and (4) cardionephritic. 4. Hydrocele fluid. CUTANEOUS EFFUSIONS. TABLE I. Cutaneous Effusions. Case No. Inco- ; Total agulable protein. nitro* yen. Total globu- lin. Euglob- ulin. Pseudo- ... globu- 1 -A^u lin. 1 mm- Chlo- rides. : Total | solids. Ash. Ratio of globulin to albu- min. Per cent, of globulin in pro- Gm. per 100 c.c. of fluid. tein. Nephritis. 4 0.098 0.004 0.080 0.048 O.O32 0.018 j 0.406 1.230 0.980 1:0.24 81 44 O.171 0.162 O.IO4 O.O91 0.095 ' 0.397 1:0.60 56.1 29 0.145 0.063 O.079 O.O24 o-°55 0.066 0.433 I-3S7 0.870 i:o.84| 54 Cardionephritis. 14 0.462 0.035 0-155 0.032 0.123 0.307 0.412 1-515 0.950 1:2.5 28.5 70 0.II9 0.035 0.043 0.018 0.025 0.076 0.420 30 0.053 0.0l8 0.082 0.400 18 The six cutaneous fluids (table I), of which three are of nephritic and three of cardionephritic origin, have certain features in com- 3 Epstein, Jour. Ex per. Med., 1912, xvi, 719.