On the combined action of cocaine and atropine in iritis / by Walter H. Jessop.

  • Jessop, Walter Hamilton Hylton, 1853-1917.
Date:
1885
Catalogue details

Licence: Public Domain Mark

Credit: On the combined action of cocaine and atropine in iritis / by Walter H. Jessop. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    drooping of lower lid ; 2.34 p.m., pupil 9 mm. when shaded, 6mm. in bright light; 2.40 p.m. pupil 10 mm., acting very slightly to light and accommodation-; 2.42 p.m., pupil II mm., does not act to light or accommodation. There- fore we have in eighteen minutes in this patient an ad maxiimnn dilatation of the pupil. To test the difference in time and rapidity of dilatation of the pupil for the same amount of atropine, the following notes were taken on the same patient:—2.46 p.m., right eye, pupil 5 mm., disc of atropine (joVtj gr.) put in eye ; 2.58 p.m., no effect ; 3.4 p.m., no effect; 3.17 p.m., pupil 8 mm., does not act to light or accommodation ; 3.22 p.m., pupil 9 mm.; 3.46 p.m., pupil 95 mm., and did not increase. Thus in eighteen minutes atropine had no effect, and in one hour the pupil was only 9.5 mm. The following cases of iritis were treated at the Central London Ophthalmic Hospital. Case i,—B. B , aged twenty-seven, was admitted Dec. 30th, 1884. Syphilitic iritis; rash eight weeks ago ; left eye inflamed six days. Left eye : great ciliary conges- tion ; iris discoloured; pupil 3'5 mm., irregular; on lower pupillary margin of iris is a gummatous mass ; T + i. Or- dered instillation of atropine, four grains to the ounce; cantharides plaster, i in. by i in.; compress; and solution of perchloride of mercury, one drachm three times a day.— Jan. 2nd, 1885: Still in pain. Left eye: ciliary conges- tion; gumma of iris the same; pupil 7 mm.; irregular; tension -f i. Two instillations of cocaine, 4 per cent, solu- tion ; pupil 9 mm., and regular, except below where gum- matous mass is ; some uveal pigment on capsule of lens, where other synechijE were ; great relief of pain. This patient continued under the same treatment, the gumma becoming absorbed ; and the pupil under cocaine and atropine 9 mm., regular, and no synechia; to be seen even