Braxy in sheep : field tests of vaccine in 1925-26 / by T. Dalling and H.R. Allen.

  • Dalling, Thomas.
Date:
[1926?]
Catalogue details

Licence: In copyright

Credit: Braxy in sheep : field tests of vaccine in 1925-26 / by T. Dalling and H.R. Allen. Source: Wellcome Collection.

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    P. V/S/f. Reprinted from The Veterinary Journal, Vol. 82, No. 8, August, 1926. r BRAXY IN SHEEP : FIELD TESTS OF VACCINE IN 1925-26.* By T. DALLING, M.R.C.V.S., J. H. MASON, M.R.C.V.S., Wellcome Physiological Research Laboratories, Beckenham, and H. R. ALLEN, M.R C.V.S. (now of the Institute of Animal Pathology, Cambridge). The results of the use of Braxy Vaccine in the field in 1924-25 have already been recorded (Dalling, Allen & Mason, Veterinary Record, 1925, No. 28, Vol. 5, p. 565, and ibid. Veterinary Record, 1926, No. 4, Vol. 6, pp. 65-66). Two further field tests were carried out during the 1925-26 season. The vaccine used was prepared as for the former experiments, and consisted of a mixture of underneutralised vibrion septique toxin-antitoxin and B. chauvoei filtrate. Laboratory tests were carried out in guinea-pigs. Tables I and II are records of such tests. Only vaccine conferring complete protection to guinea- pigs was used on sheep. The field experiment detailed in Table III was arranged by Mr. G. Howie, M.R.C.V.S., late Veterinary Adviser, Armstrong College, Newcastle, who did the actual inoculating and kept in touch with the work throughout the whole experiment. Of 2,215 hoggs injected at the end of September, 1925, and again a fortnight later, 37 or 1-6 per cent, died, while of 504 hoggs uninoculated and kept under exactly similar conditions as the inoculated, 36 or 7 • 1 per cent. died. The second held experiment (see Table IV) was carried out under similar conditions. We ourselves inoculated the hoggs. This experi¬ ment is of special interest because of the groups of hoggs which received the popular “ pig-dung treatment and which were kept on the same farms and under exactly the same conditions as the inoculated and control sheep. The “ pig-dung ” method of treatment is largely used in the Braxy districts of .Scotland and England. A full description was given by Gaiger (Journ. Comp. Path, and Therap., 1922, Vol. XXXV, Pt. 4, pp. 251-2). The net results of this second experiment * The tests were carried out from the Wellcome Physiological Laboratories.