Paralysis agitans and sarcoma : report of a case, with autopsy / by Charles L. Dana.

  • Dana, Charles L. (Charles Loomis), 1852-1935.
Date:
[1899?]
Catalogue details

Licence: Public Domain Mark

Credit: Paralysis agitans and sarcoma : report of a case, with autopsy / by Charles L. Dana. Source: Wellcome Collection.

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    were diagnosed as sarcoma, increased and added to the exhaustion of the patient, who died finally of exhaustion after his illness had lasted eight years. Post-mortem examination was made by Dr. Onuf, who carefully pre¬ served the cord, brain, and parts of the sympathetic in formalin, alco¬ hol, and in Mueller’s fluid. The post-mortem, outside of the nervous centres, showed no lesion of importance except the cutaneous sarcoma. 1 Fig. 1. 2 1. Anterior horn cell, second lumbar, showing central pigmentation. 2. Second lumbar, lateral displacement of nucleus. 3. Anterior horn cell, upper dorsal, central pigmentation. 4. First dorsal, vacuolation loss of nucleus. (Nissl stain. 1/12 objective.) (Muskins.) Examination of the Spinal Cord. Nissl stains were made by Dr. Muskins of the sections taken from the mid-cervical, upper dorsal, third and fourth dorsal, seventh dorsal, middle lumbar, and upper sacral regions. These showed very striking degenerative changes in the cells of the anterior horns. The changes consisted in marked pigmentation of the cell-body, chromatolyses, loss and displacement of the nucleus, atrophy, and loss of some of the dendrites. The absence of or defect in dendrites is common (Fig. 1). The pigmentation occupied, in some