Trichinosis : a clinical study of fifty-two sporadic cases / by W. Gilman Thompson.

  • Thompson, W. Gilman (William Gilman), 1856-1927.
Date:
1910
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Licence: In copyright

Credit: Trichinosis : a clinical study of fifty-two sporadic cases / by W. Gilman Thompson. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    40,200. Polynucleosis varied from 28 to 87.5 per cent. The lym- phocytes varied from 4 to 20 per cent. Attention was first called to the high percentage of eosinophiles in the blood of patients having trichinosis by the researches of W. S. Thayer and Thomas R. Brown,4 and it has proved of great diagnostic importance. This percentage was above 20 in thirty-one cases, or considerably more than half the series; it was above 40 in almost one-fourth of the cases, and the highest records were two cases giving 60 per cent., one 52, one 74, and two 81 per cent. In one of the latter the full blood picture was as follows: Polynuclear cells . Large lymphocytes Small lymphocytes Large mononuclear Eosinophiles . 14 1 3 1 81 100 In another case, with phenomenally high eosinophilia the blood picture showed: Polynuclear cells 28.6 Transitional cells 0.0 Large mononuclear cells 0.0 Lymphocytes . n.4 Uasophiles 0.0 Eosinophiles 60.0 100.0 In another case there were 28,750 leukocytes, with the following differential count: Polynuclear cells 16.5 Lymphocytes 5.5 Transitional 4.0 Eosinophiles 74.0 100.0 In repeated examinations in this case the eosinophiles rose in number as the leukocytosis declined. C. Stauble noticed this rela- tionship in experimental trichinosis in animals. In an experimental research in guinea-pigs, this author5 * produced eosinophilia of 52 per cent, with artificially induced trichinosis, and Kerr8 reported a case in a man with 86 per cent, of eosinophiles. T. H. Dexter7 reported cases with eosinophilia up to 68 per cent. H. Albert and H. W. 4 Lancet, 1897, and Jour. Exper. Med., 1898, No. 3. 4 ‘ 'Trichinosis/’ Weisbaden, 1909. 8 Phila. Med. Jour., August 25, 1900. 7 New York State Jour. Med., March, 1910, vol. x, No. 3.