Chemical examination of Ipomoea purpurea / by Frederick B. Power and Harold Rogerson.

  • Power, Frederick B. (Frederick Belding), 1853-1927.
Date:
[1908?]
Catalogue details

Licence: In copyright

Credit: Chemical examination of Ipomoea purpurea / by Frederick B. Power and Harold Rogerson. Source: Wellcome Collection.

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    ether removed. A small amount of a dark red oil was thus obtained which, on standing for some time, became solid. This solid sub¬ stance was dried on a porous plate and crystallized from hot water, when it separated in fine, long needles, melting at 100-101° C. It consisted of a further small amount of the new acid which is de¬ scribed below. The above-mentioned acid filtrate, which had been extracted with ether, was treated with baryta for the removal of the sulphuric acid, and the filtrate evaporated under diminished pressure to the con¬ sistency of a thick syrup, the amount of which was 18 grammes. This syrup readily reduced Fehling’s solution on heating, and yielded ^-phenylglucosazone, melting at 215° C., thus indicating the pres¬ ence of glucose. It also contained a readily soluble organic acid, which could not be separated from the sugar. Isolation of a New Dikydroxymonocarboxylie Acid, Ipurolic Acid, C13H25(OH)2 • C02H. The cake of brown resinous matter obtained by the treatment of the alcohol extract of the resin with dilute sulphuric acid, as above described, was dried on a porous plate, then dissolved in alcohol, the solution mixed with purified sawdust, and the mixture, after being thoroughly dried, extracted successively in a Soxhlet apparatus with light petroleum and ether, after which nothing remained on the sawdust. The petroleum removed about 2 grammes of an oily substance which was soluble in a solution of sodium carbonate and the fixed alkalis, and on acidifying these solutions it separated in its original form. On boiling this oily product repeatedly with large volumes of water, filtering the liquids while hot, and allowing them to cool slowly, a small amount of a colorless, crystalline substance was deposited. This melted at 68° C., and was apparently identical with a hydroxylauric acid, which was subsequently obtained in larger quantity, as will presently be described. The subsequent extraction of the brown resinous matter with ether yielded about 5 grammes of a viscid liquid, which solidified on cooling. This solid substance was dissolved in a dilute solution of sodium hydroxide, when, after standing for same time, a product separated which appeared to be crystalline. The solution was there¬ fore diluted with water, heated with a little animal charcoal, filtered, and concentrated, when, on cooling, the whole solidified to a crys'.