Upon the virulence of the bacillus of bovine and human tuberculosis for monkeys / by Allan Macfadyen, M.D. Edin. (From the laboratory of the Lister Institute of Preventive Medicine.).

  • Macfayden, Allan, 1860-1907
Date:
[1903?]
Catalogue details

Licence: In copyright

Credit: Upon the virulence of the bacillus of bovine and human tuberculosis for monkeys / by Allan Macfadyen, M.D. Edin. (From the laboratory of the Lister Institute of Preventive Medicine.). Source: Wellcome Collection.

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    the guinea-pig. A certain number of the animals died in two or in ten days after feeding with bovine and human tuberculous material. Normal human sputum did not pro¬ duce this effect and the result suggested some form of intoxication. The monkey fed thrice, twice, or once with the bovine material succumbed to a general tuberculosis in about from one to two months, and fed with the human material the same results and fatal effect were produced in about the same period of time. The young monkey proved to be equally susceptible to the bovine and human strains of the tubercle bacilli. The striking difference in the effects produced occurred in the digestive tract. Intestinal lesions were found in the case of every monkey that had been fed with human tuberculous material, whilst none of the monkeys fed with the bovine material presented any evidence of tuberculous ulcers in the intestine. Within the limits of these experiments it would appear that virulent bovine tubercle bacilli may pass through the intestinal wall in large numbers without any detectable lesion of the gut being produced. It would also appear that a food tubercu¬ losis can be as readily brought about by the bovine as by the human strain of the tubercle bacillus in the young monkey. Chelsea, S.W. Printed at The Lined Office, 423, Strand, W C