Selected monographs on dermatology / P.G. Unna [and others].

Date:
1893
Catalogue details

Licence: Public Domain Mark

Credit: Selected monographs on dermatology / P.G. Unna [and others]. Source: Wellcome Collection.

    491/636 (page 473)
    endowed with exanthematogenic properties ; while the eruptions produced by cubebs are quite rare, those which follow the ingestion of copaiba are comparatively frequent. They were first described by Montegre in 1814, and after- ward by Ricord, ten years later, under the designation of erytheme des resineux. Bazin differentiated the clinical features of the balsamic eruptions, and to his admirable description little has since been added. In some cases, the eruption appears soon after the adminis- tration of the drug ; in other cases, not until after it has been continued for some days, almost always by the eighth day. The copaiba rash manifests a predilection for certain regions, as the wrists, ankles, knees, hands and feet, breast, and abdomen, sometimes it is general, occupying the entire surface of the body. A number of eruptive elements have been met with, but erythema and papules are by far the most common. The erythematous and papular form.—This is character- ised by rosy or bright-red spots, the hyperaemia disappear- ing on pressure. Its favourite seat of development is around the articulations. The patches are usually rounded, some- times irregular, not elevated above the surrounding skin, separated from each other by interspaces of perfectly normal skin, and sometimes coalescing, forming patches of con- siderable size. Certain observers have described miliary and scarlatina-like eruptions with oedema of the subcutaneous cellular tissue. It is accompanied with itching, which may be very intense. It usually recedes promptly with the ces- sation of the medicine, the spots gradually fading and dis- appearing with slight desquamation. If the use of the drug be continued, the hyperaemic spots may develop into papules, or the rash may be papular from the first. Beren- guier describes a case of eruption from cubebs, in which the lesions were miliary, but uniting in many places, forming finger-nail sized elevations above the surface of the skin. The eruption spread over the face, arms, and trunk, less abundant over lower extremities. It disappeared with a slight branny desquamation in a few days after stopping the use of the medicine. Weiss gave a young man twenty