Selected monographs on dermatology / P.G. Unna [and others].

Date:
1893
Catalogue details

Licence: Public Domain Mark

Credit: Selected monographs on dermatology / P.G. Unna [and others]. Source: Wellcome Collection.

    484/636 (page 466)
    The urticarial form.—The eruption may present itse with the typical wheals of urticaria. In twelve of the casi the eruption was described as urticarial with oedema, puffiness of the face/' &c. In this class of cases there more or less oedema of the face, and the subjective senss tions of burning, tingling, and itching are quite distressing The general features of the following case are typical c this form. In November, 1875, I had occasion to prescrit sulphate of quinia, in two-grain doses, to a gentlema suffering from some bronchial trouble. He took the firs dose late at night on going to bed. Soon after he bega to experience a feeling of oppression in his chest and sensation as if his throat were filling up, accompanied wit the most intolerable burning and itching over the whol surface of the body. When I saw him the face was cede matous, and the entire surface was hyperaemic, and covere with wheals, most abundant about the face and neck. Thes symptoms subsided during the day, and I advised him t take another dose of the quinine the succeeding evening Its repetition was followed by a redevelopment of the urti carial rash, and I now suspected that the two might stau in the relation of cause and effect. I gave no more quinine and his cutaneous troubles speedily vanished. The patient who was a retired physician, was as much surprised at thes unusual effects of the medicine as myself. He had former! practised medicine in a malarial district, and had been ac customed to take large doses of quinine without experiencing anything beyond its ordinary physiological effects. Twi years later he suffered from malarial trouble. Remember ing his former unfortunate experience, he did not at firs take quinine, but, curious to test his vulnerability, he finalh decided to try it in one-grain doses. In less than an hou after taking the first dose he had a violent attack of urti caria, which affected the mucous membrane of the throa and fauces, as well as the entire surface of the body. The papular and vesicular forms.—In a few cases, th< eruption was described as papular1 or vesicular in character skin was quickly restored to its normal condition, and the boy was provei to have the idiosyncrasy towards quinine.—T. C. P. 1 In a case described by Buch reddish, somewhat raised, erythematou