On hereditary diabetes insipidus : with special regard to a sex-linked form / by Hans Forssman.

  • Forssman, Hans (Hans Axel), 1912-
Date:
1945
Catalogue details

Licence: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

Credit: On hereditary diabetes insipidus : with special regard to a sex-linked form / by Hans Forssman. Source: Wellcome Collection.

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    22 HANS FORSSMAN return; the diuresis and water consumption remain somewhat higher permanently. Transitory diabetes insipidus has also been observed by Lévy-Solal (cited from Henriet 1936) in a molar pregnancy. In one of Pribrsky's (1934) cases, diabetes insipidus appeared for the first time in association with the extirpation of a tumour of the adnexa, disappeared about a month after the tumour had been extirpated, and subsequently recurred in connection with 2 pregnancies. Diabetes insipidus gravidarum has been mentioned three times in connection with hereditary diabetes insipidus. Gänsslen and Fritz (1924) described the following strange case: A healthy woman married a man with diabetes insipidus, who belonged to a family that had a dominantly inherited form of the disease. The woman herself was healthy, and as far as is known there were no diabetes insipidus genes in her family. During her first pregnancy she became so intensely thirsty that she appeared to have contracted her husband's disease. When born, the child had diabetes insipidus. The phenomenon was not repeated in a later pregnancy; this time the child was healthy. Marinesco (1895) published a case of 2 brothers with diabetes insipidus, of whose parents it was said: 'Les parents ne pré¬ sentent pas d'affection similaire; cependant la mère prétend, que pendant sa grossesse elle avait grand soif et urinait beau¬ coup'. Wolff (1903) describes a man with diabetes insipidus, who had two brothers similarly afflicted. 'Der Patient macht die interessante Angabe, dass die Mutter harnruhrkrank war, während sie mit den jüngsten drei Söhnen schwanger war; auch jetzt soll sie noch an der Krankheit leiden und täglich c:a 4 Liter Urin ausscheiden'. The two latter passages from the literature are the only ones the author has found which agree fully in their treatment of the phenomenon which, in the present work, is described in numerous conductors of diabetes insipidus. In connection with the pathological increases of urine during pregnancy, different authors (Klaften 1927, Momigliano 1929, Novak 1917, Schellenberg 1930, and others) have pointed out