Tyrosine protein kinase Src,a proto-oncogene
- T.Blundell & N Campillo
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Description
Molecular model of side close-up of the proto-
oncogene tyrosine- protein kinase Src (PDB
code:1FMK), which is maintained in the inactive
state by intramolecular interactions of SH2 and
SH3 domains. The ribbon diagram shows the
auto-inhibitory phosphotyrosine 527 bound to the
SH2 domain as a ball-and-stick model.