Silencing, heterochromatin, and DNA double strand break repair / by Kevin D. Mills.

Boston : Kluwer Academic Publishers, [2001], ©2001.

viii, 122 pages : illustrations ; 24 cm

Includes bibliographical references (p. [87]-114) and index.

Yeast Silencing -- Silent HM loci -- SIR complex -- RAP1 -- ORC -- Histones -- Telomere silencing -- Telomere structure -- DNA Damage Repair -- Homologous recombination -- Single strand annealing -- Post replication repair -- The RAD6 epistasis group -- The RAD5 recombination regulator -- Nonhomologous end-joining -- Cell cycle checkpoint control -- Recent Findings -- Identification and characterization of high-copy antagonists of silencing in Saccharomyces cerevisiae -- Results -- MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double strand breaks -- Results -- The antisilencing gene ASF1 is required for resistance to DNA damage -- Results -- DNA repair -- Role of SIR complex -- Role of ASF1 -- Model for heterochromatin response -- Implications and questions -- Procedures -- Yeast strains -- Oligonucleotides.

Copy 1. Donor: Wellcome Trust Sanger Institute.