On an antidote at once for prussic acid, antimony, and arsenic / by Messrs. T. and H. Smith.

  • Smith, T.
Date:
[1865]
Catalogue details

Licence: Public Domain Mark

Credit: On an antidote at once for prussic acid, antimony, and arsenic / by Messrs. T. and H. Smith. Source: Wellcome Collection.

Provider: This material has been provided by The University of Glasgow Library. The original may be consulted at The University of Glasgow Library.

    8/12 (page 6)
    Ilrrae OfU .)Mir.f.!^iv) •,(! --/Jl '\\ bin: .i!';!;r!TOl=; oJi fii bur j'l t.l;j'iil;< n-u,i<^.,.; t^rr thLeJiqiiid comiQ^ da-,<3iiQpSii reaii(>tfe^thet ailasa ifpom ithet clotb iintq> a. cleE^ii moitar, and then rub it; ittlio a smfiiJthiioraara jnatll a difctlc* wdtet.ii The* aBtidfftq is!.now ;ready.jfqr Mse, laiad isfrOnly^onttatninMtediwitlij afq-aaiitityi ofi chloi-icle o^magnesuuii,;altogetljeriin&i^ftilijcaiat.! iiffibe ,whole;operation.'canhen easily .finisliea inabowt.five(mioutes.i•..\,-n-nvr, ■yn-i\ yuLMuf-.v I.iii<.il3 If it should be consideredi^necessafcyidio-^I^Bt ridl'eatlrtilyiof; titeldhlorideqa^ magnesium, filtration can be adopted, and ithe mixed oxide- of iron'and uisl^^- nesiawashed till the washings, come away itast'eless; > In/conaequenoe.ofifche' hydrate being mixed wjthima^nesia, th&itiltratiionf.ia vpijy napid/nn iii .b-j?!; ad It would be a great mistake-to think -that. maa;iiiesia!;it8elfiic6Mdiaot asiaBd antidote- to arseuious acid ;. any one Caa prove th-is fdr himself by the ifoUoWwI iug exiierimeut:—Dissolve a quantity ofnsulphate. of magnesia ,' sufficient to:; give -8©: grs. of i magnesia, precipitate with aqua .Ipotafssaji, filter aiid -wash' thoroughly the pulpy hydrate of magnesia;; miiSinose with tiie magnesia the' solution of 2i grs. of ar^seuious acid,! lahd^r afterithorpu^i and;Gontiuii^d agitation of the mixture, throw ;the wholelonito^i^ffltec ;. itheifiifci^e!vrUli give' at once sulphuret of arsenic on aciduiation witjh' bydrochlorie ^aci'd and addi''] tion of sulphui'etted hydi'ogen/ The same quantity of properly: pt^^pat^d peroxide of iiou, iulhe formof hydrate, would almost abianc^'baWiPemar&ii!' completely 10 gra. of ai'senious aoid fromisolution. ' n-i-iff/o iiJi —uilir/ on \o t.We here introduce a literal tx-aBskbiou of Bunsen's'original pip^i^, AS'M^ has not,, so fat as-we are awai-e, yet appeared iii t3ieJ.'ilPh£to<iiatee«'tiealirotjW^l nal,' and because'of itBsTialue and ibrevity;^ isiAii arAi axis suiiljon stjw slnam Ffilii isi long .since J haiveibeeBrnledfo tiieiobservation'tha't a iolutibaof'-arsehibnsticid- is,precipitated ia a manner so oompletcfby the liydrated peroxide- of iron 'receatly 'pre-'' cipitated and suspended in water, that a curreiit of sulphln-etted hydrogen directed through the liquid, filtered and acidulated with a small quantity: of, iydrocliloHcncid, i no longer presented the least,tiiace,of,arsenipus,f*oid.. ,1 ha,ve, found that if to this., body some drops of ammonia tje aijded, an4 if,it,then be digested.atia. gentle,heat with,: arsenious acid reduced to an impaipabte pp,>Ydei:, it transforms this last ,suhstanqe ,ypry, , quickly ihto'a basic arSenite'O^peroxide of iroii, which is altogether insolub'^e, . .^serie?,-'. of experiments, founded on this observation has produced iu nie the firm c'dnTictioh that' this body'Combines the taost fatdiirable conditions' as ah antidote against the poisonous action of arsenious acid, both in'a solid state and in' solutioD. Dr. Berthelot has very willingly, atmyirequest, iacted in concert with- me iti\the' exaraiiisitioh bf :thiS stibjlitl?^ uiider all its aspects, and inmakiogittheobject 'of mote dav^eful efxp^riinetft's.' ' 'i'' '^ o'ti'lfhe results of this examinaiaon have gone much beyond our exptfctfttiofls,' aiadibaV^'; confirmed pur gi^rsuasipn that the.; hydrate- of peroxide of iron is d better antiddte!foJi arpeuious acid, both solidand dissolyedj than Albumen is foricorrosive-sublimateJ I .tiKiiii; (i^'^ouug dogs, less thap a.foot, jjj,height;,, to whichi, we had given from ^.to S- gi-alns • o^arsenipus acid reduceti.in'to, fipe powder (and. aftef ,^xhibitiou of the hydrate, a ligur; tiwe.having been appliejJ'^'|;p,.the.|Cesoph3gus tpjprevent .vomiting), lived imore tlinaial,; wWk,' vfitliout presenting, eitheir' during' life or on dissection, tlic slightest^t|-jice,'9(f,iji;^9,-,', nipal poisoning. • r- i ■ ^ ' ' '// ' T«/jTi^ei%iYieriti'^^h^feivl*bte,'^a^'iAip mwwi\^mk iiwwrio'R^M^ ye-o pAvatioil of 'both'Mm''4na'dhnk;'iii iHry smaU' c^Viriufitv—coritbiried liiiiiosl' the' 'wl'iole r of *hoiarsenious acid, in thtsfOrnt'ofibaiic ar.^^nite of peroxide o^ ii■bu.,b^it, contained'not^ a trnce of free arscuions acidiii'Weiha-^e cb'nViucfeti 6il*-SelV6^'Iw eipeHiniiits t)^8tijniid£' that aiq,imiydtyiof hydrate 6fiFo;,iOj,i answeriug'to'fr6mi2't<!) i'draiChiTis'o'f'Fe.l03,'«itife<f^^ with 16 drops of ammonia, is sufficient to transformvin.'the) Storiach'8'tO'MigrS. tJf'VfrSiy* powdered arsenious acid into insoluble basic arsenite. . . '•It is, besides, easy to see that we might, in cases of poisoning bv arsenic,,administ^ t MS'bodytin p^oportioiis much more- considerable,' with 'oi-Wilhbikaftufiiinia, dithiir by thfe 'taoiith'br'by injection, fiihce the hydrate of Fe„ 0.„ being a body :iiltogether insoluble m wdlfer, fekercises' absolutely 'no action on the 'aiiimal economy' ...oijuloir The ammonia above recommended by Bunscn can be of no use unless there