Human genome epidemiology : building the evidence for using genetic information to improve health and prevent disease / edited by Muin J. Khoury [and others].

Date:
2010
  • Books

About this work

Publication/Creation

Oxford ; New York : Oxford University Press, 2010.

Physical description

xxiii, 676 pages : illustrations ; 25 cm

Contributors

Edition

2nd ed.

Bibliographic information

Includes bibliographical references and index.

Contents

Human genome epidemiology: the road map revisited -- Principles of analysis of germline genetics -- The public health genomics enterprise -- Navigating the evolving knowledge of human genetic variation in health and disease -- The global emergence of epidemiological biobanks: opportunities and challenges -- Case-control and cohort studies in the age of genome-wide associations -- The emergence of networks in human genome epidemiology: challenges and opportunities -- Design and analysis issues in genome-wide association studies -- The challenge of assessing complex gene-environment and gene-gene interactions -- STrengthening the REporting of genetic association studies (STREGA)-an extension of the STROBE statement -- Integration of the evidence on gene-disease associations: methods of HuGE reviews -- Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases -- Colorectal cancer -- Childhood leukemias -- Bladder cancer -- Type 2 diabetes -- Osteoporosis -- Preterm birth -- Coronary heart disease -- Schizophrenia -- Mendelian randomization: the contribution of genetic epidemiology to elucidating environmentally modifiable causes of disease -- Evaluation of predictive genetic tests for common diseases: bridging epidemiological, clinical, and public health measures -- The evaluation of genomic applications in practice and prevention (EGAPP) initiative: methods of the EGAPP working group -- Rapid, evidence-based reviews of genetic tests -- Role of social and behavioral research in assessing the utility of genetic information -- Assessing the evidence for clinical utility in newborn screening -- The role of epidemiology in assessing the potential clinical impact of pharmacogenomics -- The human epigenome and cancer -- The use of family history in public health practice: the epidemiologic view -- Cytochrome P450 testing in the treatment of depression -- A rapid-ACCE review of CYP2CP and VKORC1 allele testing to inform warfarin dosing in adults at elevated risk for thrombotic events to avoid serious bleeding -- Hereditary hemochromatosis: population screening for gene mutations.

Languages

Where to find it

  • LocationStatus
    Medical Collection
    QZ50 2010H91
    Open shelves

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Identifiers

ISBN

  • 9780195398441
  • 0195398440