A history of immunology / Arthur M. Silverstein.

  • Silverstein, Arthur M
Date:
2009
  • Books
  • Online

About this work

Description

Written by an immunologist, this book traces the concept of immunity from ancient times up to the present day, examining how changing concepts and technologies have affected the course of the science. It shows how the personalities of scientists and even political and social factors influenced both theory and practice in the field.

Publication/Creation

Amsterdam ; Boston : Academic Press/Elsevier, 2009.

Physical description

1 online resource (xxi, 530 pages) : illustrations

Edition

2nd ed.

Contents

Theories of acquired immunity -- Cellular vs. humoral immunity -- Theories of antibody formation -- The generation of diversity: the germline/somatic mutation debate -- The clonal selection theory challenged: the immunological self -- The concept of immunologic specificity -- Specificity continued -- Horror autotoxicus: the concept of autoimmunity -- Allergy and immunopathology: the "price" of immunity -- Anti-antibodies and anti-idiotypic immunoregulation: 1899-1904 -- Transplantation and immunogenetics -- Magic bullets and poisoned arrows: the uses of antibodies -- The royal experiment: 1721-22 -- The languages of immunologic dispute -- The search for cell-bound antibodies : on the influence of dogma -- 'Natural' antibodies and 'virgin' lymphocytes: the importance of context -- The dynamics of conceptual change in immunology -- Immunology in transition 1951-1972: the role of international meetings and discipline leaders -- The origin of subdisciplines: (ocular immunology; pediatric immunology; immunophysiology) -- Immune hemolysis: on the heuristic value of an experimental system -- Darwinism and immunology: from Metchnikoff to Burnet -- The end of immunology? -- Appendix A1. The calendar of immunologic progress -- Appendix A2. Seminal discoveries -- Appendix A3. Important books in immunology, 1892 -- 1968 -- Appendix B. Nobel Prize highlights in immunology -- Appendix C. Biographical dictionary.

Bibliographic information

Includes bibliographical references and indexes.

Type/Technique

Languages

Permanent link

Identifiers

ISBN

  • 9780080919461
  • 0080919464