Cases of intra-cranial tumour / by Byrom Bramwell.

  • Bramwell, Byrom, Sir, 1847-1931.
Date:
[1878-1879]
Catalogue details

Licence: Public Domain Mark

Credit: Cases of intra-cranial tumour / by Byrom Bramwell. Source: Wellcome Collection.

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    very much flattened, and the sulci effaced. The brain weighed 2 lbs. 14 J oz. On cutting into the cerebral substance, nodules of new growth were found in the following situations:— A pyriform nodule, size f inch by J inch, in the extremity of the first left frontal convolution, where it turns over to become the supra-marginal convolution. 2dj An irregular-shaped nodule, measuring inch in length by f of an inch in breadth, in the left gyrus fornicatus, at the junction of its middle with its posterior third. 3<i, An irregular nodule slightly larger than the preceding nodule in the corresponding part of the right gyrus fornicatus. This nodule extended upwards through the gyrus fornicatus and the supra-marginal convolution to within a quarter of an inch of the vertex of the hemisphere. Nodules two and three were joined by a connecting band of new growth, which rested upon the posterior part of the corpus callosum. An oval nodule, f of an inch in length by \ an inch in breadth, in the tip of the left occipital lobe. An irregular nodule, | of an inch in length by | of an inch in breadth at its broadest part, in the angular gyrus of the right side. Q>th, A large round nodule, inch in diameter, in the position of the left corpus striatum, which was almost entirely destroyed by it. All the nodules of new growth presented the same character. They were of a yellowdsh colour, very firm in consistence j none of them presented any trace of softening. They were separated from the surrounding healthy brain tissue by a narrow line of softened material. After some days’ immersion in spirit all the nodules could be easily separated from the surround¬ ing brain tissue. On microscopical examination they were found to present the usual characters of the tubercular brain tumour. The line of softening between the nodules and the brain tissue proper contained numerous bloodvessels. The fibrous element in the nodules was greater than is usually seen in this form of growth. The vascularity of the brain seemed normal. The ventricles were normal. No nodules were found in the cerebellum. The upper portion of the spinal cord was placed in hardening solution, but unfortunately was mislaid; a circumstance which 1 much regret, for one of the most interesting points in the case would have been the course of the degenerated fibres in the cord. In the lower lobe of the left lung there was a large dry caseous mass. Some gray tubercles were scattered throughout the rest of the left lung. A few were also situated in the apex of the right. The peritoneum, intestines, and other organs of the body were normal. The left wrist joint was in a state of scrofulous degeneration.