A handbook of local therapeutics / edited by Harrison Allen.

Date:
1893
Catalogue details

Licence: Public Domain Mark

Credit: A handbook of local therapeutics / edited by Harrison Allen. Source: Wellcome Collection.

    196/554 (page 184)
    S. D.). It has an unpleasant odor which is compared to that of the nil of K.-ff i Chinoline is sparingly soluble in cold water, Jre so in hot wa er In 7u'^^ and. ^ ^^^.^ ^^^^^^o.:i:zlx^: also dissolves camphor and resins. It forms crystalli.able salts with acids the nrate now being a commercial article. (U. S. D.) Chinoline is antiseptic. In this respect it is an agent - stronger anti septic than sodium salicylate, carbolic acid, quinine, boric acid, sulpha^l of copper, or alcohol. In four-tenths per cent, solution it arrests the putrefaction of blood and the curdling of milk. By a one per cent solution the coagulability of the blood was completely destroyed. (U.' General Surgery.-Domat (/ourn. de Med., Paris, June lo, 1888) regards a 1-150 solution of the tartrate of chinoline as a very useful injection in Gonorrhcea. Diseases of the Ear, Throat, etc.-Chinoline is recommended in the treatment of Otorrhcea. C. H. Burnett advises its union with salicylic acid in the proportion of one of chinoline to ten, or of boric acid one to fifteen. Its use has been advocated also in a five per cent solution in the local treatment of Diphtheria. Chinoline has been employed in the treatment of Gangrene of the . dental pulp, by introducing small plugs of cotton soaked in a twenty per cent, solution of Merck's tartrate of chinoline. Over this is placed a piece of absorbent cotton sprinkled with powdered chinoline. The dressing is changed every other day, the cavity being washed out with a solution of permanganate of potassium. (London Med Times, June ic 1885.) ^' CHLORAL. Hydrate of Chloral. Chloral Hydrate. The United States Pharmacopoeia incorrectly calls the hydrate of chloral chloral. So that, under the name of chloral, the hydrate is always supplied in the United States. The name chloral should be applied to an anhydrous product. Hydrate of chloral is found in the market in two forms—the crystals and the plates. The crystalline is to be preferred because of its greater purity, though for external medication, while less active than the crystalhne, that of the plates may often suffice. Hydrate of chloral volatilizes in the air and, consequently, should be kept in well-stopped bottles. The official chloral is « freely soluble in water, alcohol, ether, and also soluble in four parts of chloroform, in glycerin, benzol, benzin, bisulphide of carbon, fixed or volatile oils. It liquefies when mixed with carbolic acid or with camphor. (U. S. P.) For the property of union between chloral and camphor see Cam- phorated chloral. Chloral is antiseptic, anaesthetic, and vesicant. General Surgery.—Owing to the irritant properties of chloral it has