A handbook of local therapeutics / edited by Harrison Allen.

Date:
1893
Catalogue details

Licence: Public Domain Mark

Credit: A handbook of local therapeutics / edited by Harrison Allen. Source: Wellcome Collection.

    102/554 (page 90)
    in plugs saturated with a five to ten per cent, solution. A one-half per cent, solution has been used with asserted advantage in Gonorrhcea Diseases of the Ear, Nose, and Throat.-F. W. Hinkle (AT V Med Jour., Oct. ao, 1888), believes that antipyrin is a valuable adju^ vant in the treatment of Nasal Catarrh. A four per cent, solution may be sprayed into the nostril. At first a slight smarting sensation is produced, but the subsequent impression resembles that of cocaine In a recent communication to one of us, Dr. Hinkle reasserts his statement respecting the effect of antipyrin in irritable states of the mucous mem- brane. It IS a mild sedative, and free from the inconvenience and objections of cocaine. It is not contra-indicated in solutions of this agent, but appears to increase its value. The impression is less decided than is the case with cocaine, while more persistent. Subsequent observers claim that this impression is due to its absorption into the system; the effect, therefore, is not strictly local, since the internal administration of the drug produces a similar effect upon the nasai mucous membrane. Occasionally subjects will be found who cannot permit the use of antipyrin in any strength, it proving to be with them irritating. Haemostatic properties have been claimed for antipyrin. Both Hinkle and Henorque {^Gaz. hebdom., Jan. 13, 1888, p. 29) employ for this pur- pose a strength of one part to five. It appears to be especially useful in checking bleeding from a Cancerous Ulcer. B. Robinson (N. Y. Med. Jour., Sept. 24, 1887) recommends antipyrin in capsules for epistaxis, in strength of solution varying from five to fifteen grains to the ounce of water. Its analgesic effects are increased by combining with it a small portion of morphine. In this manner H. Snow {Brit. Med. Jour., Feb. 16, 1889) has employed it in the treatment of Malignant Growths of the Mouth and Tongue. Diseases of the Eye.—Antipyrin has been used with asserted good effect in clearing up Corneal Opacities. As it has been dusted on the cornea with calomel, its effects cannot be separated from those of this old standard remedy. AQUA. Water. The uses of water in the local treatment of disease are numerous. Apart from the indirect aid secured by cleansing foul surfaces, water can be employed, according to the temperature to which it is raised, to answer a variety of indications; in a word, it is a convenient means of controlling degrees of heat. Dry heat (ordinarily obtained by radiation from a metallic surface) can be maintained by passing previously heated water through flexible metallic tubes (Leiter tubes). Water exerts no specific action on living tissue ; it acts by presence, or by its temperature.