Clinical study and analysis of 1,000 cases of psoriasis / by L. Duncan Bulkley.

  • Bulkley, Lucius Duncan, 1845-1928.
Date:
1891
Catalogue details

Licence: Public Domain Mark

Credit: Clinical study and analysis of 1,000 cases of psoriasis / by L. Duncan Bulkley. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    the positive and negative aspects of the question, and the results obtained in the 322 oases are exhibited in the table V: TABLE V. HEREDITY. Male. Female. Total. Oases with anterior heredity, 14 19 33 Oases with posterior heredity, 6 1 7 Oases with no heredity, 74 62 136 Unknown or unrecorded, 137 72 209 231 154 385 Cases with parents affected, 12 15 27 Oases with grandparents affected, 3 3 6 Cases with children affected, 15 1 16 Oases with brothers and sisters affected, 27 17 44 Cases with collateral relatives affected, 4 7 11 Here we see that in but 33 cases was there>any anterior heredity recorded; of these, 27 reported the disease as having existed in one or the other of their pa- rents, and 6 patients reported a grandparent affected. In the records are found notes regarding 143 children of psoriatic parents. Of these, but 15 are recorded as having the disease, that is, only a trifle over ten percent. Oat of 291 brothers and sisters of psoriatic patients, only 41 are recorded as af- fected, while 250 escaped, a ratio of only 14 per cent.; of collateral relatives there were only 11 instances in whom psoriasis was reported, upon inquiry, to have ex- isted. It would seem, therefore, from a study of these cases at least, that heredity bears but a small share in the production of psoriasis, the proportion of instances exhibiting this certainly being not as great as could readily be found among cases of eczema, acne, urticaria, and perhaps other skin affections. The location of the lesions of psoriasis is not a little interesting, although but little practical value can be derived from the data concerning them TABLE VI.-—LOCATION OF PSORTASIS. * Location. Males. Females. Total.. General, 123 90 213 Head, 92 65 157 Body, 90 49 139 Upper extremities, 97 87 184 Lower extremities, 84 57 141 Genitals, 14 4 18 Palms and soles, 9 4 13 The figures in regard to this feature are recorded, the various locations being noted where the disease either existed exclusively or appeared. Thus it was found to be diffused in all parts of the body in 213 instances; the head was affected in 157, the body in 139, the upper extremities in 184, etc. Psoriasis very rarely affects the palms and soles, but 13 instances having been noticed among the cases here analyzed. The complications of psoriasis are often very interesting and at times very im- portant; appearing, as it does, at all ages and often lasting during many years, if naturally often co-exists with many other affections and conditions of the body. As is well known, during certain general or exhaustive diseases psoriasis will