Cancer research today : immunology and the host response.

Date:: 1974

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Credit

Cancer research today : immunology and the host response. Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). Source: Wellcome Collection.

About this work

Description

This programme is presented as a dialogue, dealing with the specific antigenicities of tumour cell populations. The antigens are of three broad types, those associated with "viral" tumours, those in chemically-induced tumours, and "embryonic" antigens. The methods of detection of the antigens are discussed, with emphasis on the different results obtained with human tumours and the lack of suitable in vitro test systems other than with experimental animals. The failure of immune responses to dislodge tumours is discussed, as well as various means by which an anti-tumour response might be augmented in favour of the patient. 7 segments.

Publication/Creation

London : University of London Audio-Visual Centre, 1974.

Physical description

1 encoded moving image (36.04 min.) : sound, black and white.

Series

Contributors

Duration

00:36:04

Copyright note

University of London

Terms of use

Unrestricted

CC-BY-NC

Creative Commons Attribution-Non-Commercial 2.0 UK: England & Wales

Language note

In English

Creator/production credits

With Dr AJS Davies and Professor Peter Alexander. Made by University of London Audio-Visual Centre. Made for British Postgraduate Medical Federation.

Notes

This video is one of around 310 titles, originally broadcast on Channel 7 of the ILEA closed-circuit television network, given to Wellcome Trust from the University of London Audio-Visual Centre shortly after it closed in the late 1980s. Although some of these programmes might now seem rather out-dated, they probably represent the largest and most diversified body of medical video produced in any British university at this time, and give a comprehensive and fascinating view of the state of medical and surgical research and practice in the 1970s and early 1980s, thus constituting a contemporary medical-historical archive of great interest.

Segment 1 Davies introduces the lecture. He and Professor Alexander are then shown seated for discussion. They explain that they are going to have a dialogue on the subject of immunology. They begin by discussing chemically induced tumours. Time start: 00:00:00:00 Time end: 00:05:35:00 Length: 00:05:35:00

Segment 2 Davies and Alexander talk about tumours induced by chemical carcinogens in experimental animals. Time start: 00:05:35:00 Time end: 00:10:32:00 Length: 00:04:57:00

Segment 3 Davies and Alexander talk about tumour-specific transplanatation-type antigens (TSTAs). Time start: 00:10:32:00 Time end: 00:16:12:15 Length: 00:05:40:15

Segment 4 The problems with relying on chemically induced human tumours developed in vitro is discussed. Time start: 00:16:12:15 Time end: 00:22:10:15 Length: 00:05:58:00

Segment 5 Davies and Alexander talk about T cells, B cells and macrophages and their relationship to cancer. Time start: 00:22:10:15 Time end: 00:26:57:15 Length: 00:04:47:00

Segment 6 Cytotoxic cells and their relation to cancer are discussed. Time start: 00:26:57:15 Time end: 00:31:20:00 Length: 00:04:22:10

Segment 7 Davies and Alexander conclude their discussion. Time start: 00:31:20:00 Time end: 00:36:04:11 Length: 00:04:00:11