On the descending degenerations which follow lesions of the gyrus marginalis and gyrus fornicatus in monkeys / by E.P. France ; with an introduction by Professor Schäfer.

  • France, E.P.
Date:
1889
Catalogue details

Licence: Public Domain Mark

Credit: On the descending degenerations which follow lesions of the gyrus marginalis and gyrus fornicatus in monkeys / by E.P. France ; with an introduction by Professor Schäfer. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

    12/30 (page 340)
    Microscopic. Pons.—Scattered degeneration can be seen in the pyramidal bundles of both sides. Medulla.—Scattered degeneration can be seen in both anterior pyramids, Spincd Cord. Cervical Region.—The degeneration occupies that part of the crossed pyramidal tracts which borders on the direct cerebellar tract, and extends from the posterior cornua towards the circumference on both sides. It is not very well marked, but occupies a similar position to that of all the other marginal cases. Dorsal Region.—In the dorsal region it is relatively less in amount, closer to the circumference, and does not extend as far forwards. Lumbar Enlargement.—It is much less in amount here, and lies in the angles formed by the posterior cornua and the circumference of the cord. Case 6.—No. of First Series. Lesion.—Kemoval of both marginal convolutions at two operations. Frontal sections through the brain show that the convolutions were completely removed, except a small strip of grey matter at the deepest part of the calloso- marginal fissure on the left side. The adjoining external surface was also Injured. Result.—The first operation on the left side produced the usual paralysis of the opposite hind limb and of the trunk. The second operation (right side) produced paralysis of the trunk and legs of the opposite side, except that the knee and hip can be feebly flexed. The animal died three months after the first operation. Degenerations Observed. Very well marked degeneration is visible to the naked eye on both sides in the crossed pyramidal tracts. Pons and Medulla.—Under the microscope sections show scattered degeneration in the pyramidal bundles and pyramids. Spinal Cord. Cervical Enlargement. — There is degeneration on both sides, extending over a large portion of the crossed pyramidal tracts, and involving part ot the region of the direct cerebellar tracts. The degeneration in the crossed pyramidal tracts is like that observed in the spinal cords of the other animals after similar lesions, although more extensive than in most cases. The region of the direct cerebellar tract* is also greatly involved on both sides. A small triangular patch of healthy fibres represents this tract, close to the posterior root exit. Dorsal Region.—The degeneration is well marked and rather more defined than in the cervical region. The parts in the direct cerebellar tracts noticed to be free from degeneration in the cervical region are still seen, and appear rather larger. * Probably the porLiou of the pyramidal tract which encroaches on the cerebellar tract.