Volume 1

Gene expression / Benjamin Lewin.

  • Lewin, Benjamin.
Date:
1974-1977
Catalogue details

Licence: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

Credit: Gene expression / Benjamin Lewin. Source: Wellcome Collection.

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    Induction arabinose 323-328 constitutivity 277,311-316 coordinate 273-274 evolution 342-344 galactose system 328-333 gratuitous inducer 274 inducer 272-274,311-316 lactose operon 272-309 level of control 272, 281-282, 291— 297, 298-299, 323, 329 negative control of 310-316 non coordinate 336 positive control of 310-316 regulator gene 271-281,310-316 repressor protein 276-278 uninducibility 277, 312, 324, 327 Joint molecule 544-548 Kethoxal 153 Lactose operon allolactose 293 catabolite repression 302 constitutivity 277,289 cyclic AMP, and 302-307 diploids of 275, 278 Fusion to trp 299 /?-galactosidase 273-274, 293, 395- 396 hybridization 282-283, 303 inducer, 274, 282, 291, 301 isolation 307-309 kinetics of expression 285, 381 lactose 294 messenger RNA 282-285, 304, 403 nonsense mutants 286, 393-396,399, 403, 405 operator 275, 278, 288-290, 291-297 permease 274 polarity 391-395 polysomes 284,299 promotor 286-287, 298, 304—307 regulator (i) gene 275, 290-291 repressor protein 276-280, 287, 290- 297 repressor synthesis 299-302 structural genes 273-274 transacetylase 274 transcription 280-285, 305-307,399, 406-407 translation 272, 284-285, 381, 390, 394-396, 399, 404, 407 uninducibility 277, 300 Lambda phage early synthesis 268-269, 365-366 exonuclease 547-548 immunity 345 immunity region 254-255, 346-347 induction 344 late synthesis 271,367 lysogeny 345, 358-359 N gene 254, 269, 345, 365-367 operators 347, 350-357 promotors 255, 347, 350-357 repression 346,360-364 repressor protein 346, 347-350, 354- 357 repressor synthesis 357-364 rho factor, and 252-255, 364-366 tof function 255, 269, 345, 361-366 transcription initiation 254,269,271, 347, 351-353, 364-367 transcription termination 269, 251— 255, 347 virulence 350, 351 Marker rescue 483 Messenger RNA— see also Transcription arginine 333 degradation 285, 384-387, 400-404 detection 40-42 DNA as 86 hybridization 262-264, 303, 329, 333, 346-347, 379-380 lactose 282-285, 304, 403 lambda 254-255, 269-271, 360-367 polycistronic 323, 329, 342, 383, 396- 406 rll T4 265-266 ribosome binding 86-89, 101-104, 389,395,397-398 RNA phages as 26, 86-89 synthetic polymers as 20-23 template, as 14, 40-42, 46 T4 phage 262-268 tryptophan 379-387,399 Methionyl-tRNA m 79-82, 89-90, 94- 96 Missense mutation 27, 166, 196, 211, 221-223 Mitomycin C 501