Volume 1

Gene expression / Benjamin Lewin.

  • Lewin, Benjamin.
Date:
1974-1977
Catalogue details

Licence: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

Credit: Gene expression / Benjamin Lewin. Source: Wellcome Collection.

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    eis/trans test 4-5, 279-280, 311 Cistron 4-5,279 Codon amino acids, and 19-26, 34, 37 frequencies 30-33 initiator 81-85, 89, 203 in vivo, use of 25-26 tRNA recognition 19-26, 83-84, 202-209, 213 Complementation 3-5 Cyclic AMP system 302-307, 315, 328, 330, 333 DNA components of 8 genetic material, as 5-7 structure 7-10,426-427 unwinding 231, 429-434, 445-446 DNA polymerase accuracy 436-440 active centres 438,517 DNA binding 517-518 E.coli I 438, 450, 457, 459-460, 462, 469, 498, 516-520, 520-522 E.coli II 460-464, 468-469 E.coli III 466-469 eucaryotic 469-470 exonuclease activities 438, 457, 459, 463, 469, 516-517 phage T4 436-438,463,469,545-547 DNA methylation enzymes 483-487, 489, 495 mutants 475-482 replication cycle, and 473, 481-482 DNA restriction enzymes 482, 483-490 mutants 475-490 recognition sites 490-495 Episomes 138, 275, 278, 424-425, 563 Erythromycin 138 Escape synthesis 340-342 Exonuclease I 443, 472, 491, 514 Exonuclease III 472 fd DNA transcription 243-244, 256- 259 5-fluorouracil 281 Formyl-methionyl-tRNA 79-84, 89-90, 94-96, 186, 188 Frameshift mutants 17-19, 23, 27, 223-225 Fusidicacid 71, 138, 377 Galactose operon 306, 328-333, 406- 407 /?-galactosidase catalytic activities 273-274, 293 complementation 396 fragments 396 mutants 274, 395 Gene clusters 138-139, 273-274, 342-343 definition 1-5, 10-13, 241, 275 frequencies 418-420 regul ator 275-281,311-316 structural 275 Gene conversion 530-534, 536-540 Genetic code codon assignments 19-26, 80-85, 202-299 colinearity 10-13 degeneracy 31 evolution 28-37 nonsense codons 12-13, 28-30, 112— 116,211-217, 220-221 triplet 13-19,21 universality 31, 204, 208 Genetic information 7, 13, 42^43 Genetic mapping deletion 12,353 electron microscope 353 fine structure 11-13 gene frequencies 418-420 heteroduplex 231-235, 309, 354 recombination, and 524-525, 540- 543 Guanosine tetraphosphate 372-377 Haemoglobin mutants 4 polysomes 47 synthesis 38-40, 47, 84 Heia cell chromosomes 423-424 nucleolar rRNA synthesis 122-125 repair of DNA 504-506 Heparin 236,245-246 Histidine operon 316-323,391 Hybridization competitive 262-264,282-283 DNA-mRNA 41-42, 262-264, 303, 329, 333, 346-347 DNA-rRNA 125-128, 368 DNA-tRNA 177, 215-217, 368