Principles of laboratory animal science : a contribution to the humane use and care of animals and to the quality of experimental results / edited by L.F.M. van Zutphen, V. Baumans, A.C. Beynen.

Amsterdam ; New York : Elsevier, 2001.

xii, 416 pages : illustrations ; 25 cm

Rev. ed.

Includes bibliographical references.

Introduction -- Legislation and animal experimentation -- Biology and husbandry of laboratory animals -- Behaviour, stress and well-being -- Standardization of animal experimentation -- Nutrition and experiment results -- Genetic standardization -- Microbiological standardization -- Diseases in laboratory animals -- Animals models -- Phases in an animal experiment -- Design of animal experiments -- Organization and management of animal experiments -- Recognition of pain and distress -- Anaesthesia, analgesia and euthanasia -- Experimental procedures -- Reduction and replacement concepts in animal experimentation -- Ethical aspects of animal experimentation -- Annex.