Cell growth and apoptosis : a practical approach / edited by George P. Studzinski.

Date:
[1995], ©1995
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About this work

Description

This Practical Approach volume is unique in describing the key concepts of cell growth and cell death, particularly by apoptosis, and in providing detailed methods to study these processes. The chapters are written by experts in the field and cover a wide range of important subject areas including cell-cycle traverse, chromosomal abnormalities detected at cell division, DNA damage, and cell death or senescence. The establishment of cell lines and optimization of cell proliferation by growth factors are also described. The result is an invaluable laboratory manual for studies of growth and its abnormalities in mammalian cells. Cell Growth and Apoptosis: A Practical Approach provides state-of-the-art protocols for studies of normal and abnormal cell growth, including cancer and other cell-proliferation disorders, together with a critical appraisal of the various methodologies in use. Its coverage of human cells will make it particularly useful for health professionals.

Publication/Creation

Oxford ; New York : IRL Press at the Oxford University Press, [1995], ©1995.

Physical description

xxvi, 269 pages : illustrations ; 24 cm.

Bibliographic information

Includes bibliographical references and index.

Contents

Measuring parameters of growth / Renato Baserga -- Cell cycle analysis by flow cytometry / Harry A. Crissman -- Analysis of Flow cytometric DNA histograms / Peter S. Rabinovich -- Determination of the cell Proliferative fraction in human tumours / Rosella Silvestrini -- Chromosome analysis in cell culture / Anwar N. Mohamed -- Assessment of DNA damage in mammalian cells by DNA filter elution methodology / Richard Berrand -- Analysis of cell death by flow cytometry / Zhigniew Darzynkiewicz -- Assays of cell growth and cytotoixicity / Philip Skehan -- Cell synchronization as a basis for investigating control of proliferation in mammalian cells / Gary S. Stein -- Growth and activation of human Leukaemic cells in vitro and their growth in the SCID mouse model / Sophie Visonneau -- Senescence and immortalization of human cells / Karen Hubbard -- Analysis of the effects of purified growth factors on normal human fibroblasts / Paul D. Phillips.

Notes

Copy 1. Supplier/Donor: Wellcome Trust Sanger Institute.

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ISBN

  • 0199635692
  • 9780199635696
  • 0199635684
  • 9780199635689