The ureides of p-aminophenylstibinic acid / by W.H. Gray [and others].

Date:
[1931.]
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Licence: Public Domain Mark

Credit: The ureides of p-aminophenylstibinic acid / by W.H. Gray [and others]. Source: Wellcome Collection.

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    glucoside group, for instance, did not die for L8 days, whereas mouse No. 7 injected with urea stibamine 55 died on the fourteenth day. It is clear. Time in days Fig. 1.—Percentage of mice dead on each day after injection of 1-5 mg. urea stibamine (B.926)—(full line) and 3-0 mg. stibamine glucoside W.3 per 20 g. mouse (dotted line). 5 + 4-+ 3 + 2 + / / / / / ]5~ 20 Time In days Fig. 2.—Average intensity of infection-number of pluses assigned daily—dead mice being reckoned as 5-f. 1*5 mg. B.926 per 20 g. mouse (full line), 3-0 mg. W.3 j>er 20 g. mouse (broken line). therefore, that there is a possibility that the difference in mean survival time is not due to a real difference in activity of the two drugs, but that the difference has arisen solely by chance amongst the animals used. To determine whether the differences shown in Table III are real differences, or merely random differences due to the variability of mice, we have applied simple statistical tests. The statistical method used is that developed by Fisher from “ Students work (Fisher, p. 109). The ratio of the difference of the average values, c