Formulary for the preparation and mode of employing several new remedies : namely, morphine, iodine, quinine, cinchonine ... / with an introduction and copious notes, by the late Charles Thomas Haden ; translated from the 'Formulaire ... par F. Magendie. Troisième édition, 1822.'.

  • Magendie, François, 1783-1855.
Date:
1823
Catalogue details

Licence: Public Domain Mark

Credit: Formulary for the preparation and mode of employing several new remedies : namely, morphine, iodine, quinine, cinchonine ... / with an introduction and copious notes, by the late Charles Thomas Haden ; translated from the 'Formulaire ... par F. Magendie. Troisième édition, 1822.'. Source: Wellcome Collection.

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    proto-hydrochlorate of tin be poured upon it a most beautiful violet-coloured precipitate is formed ; this property appertains solely to brucine.:# ACTION OF BRUCINE ON THE ANIMAL ECONOMY. The action of brucine on the animal economy is similar to that produced by strychnine, but it is less energetic. Its intensity has ap¬ peared to us in some experiments to be to that of pure strychnine^ as 1 to 12. It re¬ quired four grains (gr. 3,281 T.) of brucine to kill a rabbit. A tolerably strong dog after 4 * Strychnine, extracted from the nux vomica, when treated by the same means sometimes assumes a violet tint. Under such circumstances we may feel assured that it retains brucine ; for the strychnine from St. Ignatius’s bean and even that from the nux vomica when perfectly purified does not produce the violet colour with the proto¬ hydrochlorate of tin. f Dr. Andral jun. has lately made some fresh compara¬ tive experiments on brucine and strychnine, and he has arrived at this result that six grains of brucine are re- i quired to produce the effects of one grain of impure, and of a quarter of a grain of pure strychnine. The difference of action would therefore appear to be greater than what we had at first estimated.