Manual of serum diagnosis / by Dr. O. Rostoski ; authorized translation by Dr. Charles Bolduan.

  • Rostoski, Otto.
Date:
1904
Catalogue details

Licence: In copyright

Credit: Manual of serum diagnosis / by Dr. O. Rostoski ; authorized translation by Dr. Charles Bolduan. Source: Wellcome Collection.

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    in which agglutination was still very marked in dilutions of i: looo, and Eckhardt reports two cases of Weil’s disease in which the senim possessed equally strong agglutinating power. The cause of the jaundiee seems not to have much bearing on the subject; agglutination has been found in all forms of jaundice. By investigating a large num- ber of bacteria, Ludke has demonstrated that in many eases the agglutination affeets only typhoid bacilli. Nevertheless it must be remembered that now and then other varieties of bacteria are agglu- tinated, such as proteus and hacterinm coli. Unfor- tunately it is not yet clear to what these curious phenomena are due. The agglutination cannot be due to the bile as sueh, for this, as Ludke eould prove, usually does not agglutinate at all. Further- more Eckhardt has described a ease in which the ieteric serum agglutinated, while the bile obtained through a biliary fistula did not. And yet the bile when absorbed into the blood-serum could so change the latter that it gained agglutinating power. Ex- perimental researches in this direction, however, have not been entirely suecessful. Thus Ludke was never able to produce any agglutinating pro])- erty in serum by mixing serum with bile in a test- tube, or by injecting bile into an animal. Kohler, however, by injecting one of the bile constituents, namely taurocholic acid, intravenously into a dog