Manual of serum diagnosis / by Dr. O. Rostoski ; authorized translation by Dr. Charles Bolduan.

  • Rostoski, Otto.
Date:
1904
Catalogue details

Licence: In copyright

Credit: Manual of serum diagnosis / by Dr. O. Rostoski ; authorized translation by Dr. Charles Bolduan. Source: Wellcome Collection.

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    of one year. Kasel and Mann ^ likewise empha- size that the reaction disappears especially rapidly in children. According to Kohler,^ only a com- paratively small percentage of patients still show the reaction after a year. My own experience coin- cides with Kohler’s. It is certainly rare that the reaction remains for only two weeks after subsi- dence of the fever, though I have seen even such cases. From what has been said it follows that a patient suffering from an acute infectious disease may show a Gruber-Widal reaction which is due to a previous typhoid; and if that should have been a very mild or walking typhoid or one that was not recognized, the patient would be entirely ignorant of the attack. Hence von Luebe ^ states that the reaction is especially conclusive when after being negative in the beginning of the disease it becomes positive some time after. Quite independently of these patients who have previously had typhoid, there are sick and healthy persons in whom a Gruber-Widal reaction is demonstrable. Foremost to be considered is the fact that the serum of jaundiced patients frequently agglutinates typhoid bacilli, as was first shown by * Bcitrjige zur Lchre dor Grubcr-Widal’schen Scrumdiagno.se des Unterleibs-typhns, Mncnch. vied. Wochenschr. 1S94, No. iS. ^1. c. p. 81. 1. c.