Specification of Joseph Lawson Petingale : digestive mixtures.

  • Petingale, Joseph Lawson.
Date:
1876
Catalogue details

Licence: Public Domain Mark

Credit: Specification of Joseph Lawson Petingale : digestive mixtures. Source: Wellcome Collection.

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    Specification. I e ting ale's Improvements in Digestive Mixtures. relatively increase the pepsine beyond the proportion of the other two digestive principles, and when it is desirable to assist the digestion in the bowels the pancreatine becomes the more important constituent in the mixture, and must be increased in its proportion. But in all instances I prefer to have an admixture of at least two of these 5 principles, having found by experience that each of these materially increases the digestive power of the other. For the same reason I prefer for general purposes to have a certain amount of each of the digestive principles, and that these may exert a higher digestive power upon food, I furnish, together with the digestive compound, a dilute 10 solution of hydrochloric and lactic acids, kept separate in a suitable vessel, and not mixed with the digestive principles until the latter are to be taken, or as I much prefer it to be taken after further dilution at from ten minutes to half an hour after the digestive compound has been swallowed. 15 For generally enfeebled digestion I find a very useful proportional composition of the digestive compound to be as follows 16 parts of pepsine, 12 parts of pancreatine, and 1 part of diastase, and this may be advantageously diluted with 80 parts of good sugar of milk. The dilute hydrochloric or lactic acids furnished with the digestive 20 compound as above should be again lowered in strength until the acidity present is equal to about one per cent, of concentrated hydro- chloric acid. But I have found that when the acid solution contains greater acidity than would be represented by four per cent, of hydro¬ chloric acid the processes of digestion are arrested instead of stimulated, 25 and if a lesser proportion is taken than one per cent, of acid it will require a larger amount of such more diluted acid to accomplish the most desirable digestive action. The amount or quantity of the one per cent, solution of acid in proportion to the digestive compound used may be broadly taken as about 50 parts by weight of dilute acid to one of 30 the digestive compound. A rather larger proportion of acid may be taken when greater assistance has to be rendered to the digestion of the stomach, and somewhat less is advisable when the digestive powers of the saliva or of the pancreatic juice have to be augmented by means of this digestive 35 compound. In former combinations of the digestive principles with acids in the