Standardization of anti-dysentery (shiga) serum / H.J. Sudmersen, B.F. Runge, and R.A. O'Brien.

  • Südmersen, Henry J.
Date:
[1924?]
Catalogue details

Licence: In copyright

Credit: Standardization of anti-dysentery (shiga) serum / H.J. Sudmersen, B.F. Runge, and R.A. O'Brien. Source: Wellcome Collection.

    7/10 (page 104)
    The dose chosen as a test dose of toxin is that which when mixed with Q'025 c.c. of C.950 would kill all rabbits injected ; this dose is 0*2 mgm. Summary.—A dysentery (Shiga) “ toxin ” consisting of dried bacillary bodies is described as a standard toxin for the titration of anti-dysentery sera. The test dose of the toxin has been found by titration against a test dose of standard anti-dysentery (Shiga) serum. We are at present undecided whether further experience will lead us to prefer mice or rabbits for standardization. ADLAHD AND SON AND WEST NEWMAN, LTD., IMPK., LONDON AND DORKING. 2