Animals for research : principles of breeding and management / edited by W. Lane-Petter.

Date:
1963
Catalogue details

Licence: Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)

Credit: Animals for research : principles of breeding and management / edited by W. Lane-Petter. Source: Wellcome Collection.

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    contents xiii 7. Genetics of the Mouse mary f. lyon I. Introduction 199 II. Uses of Special Genetic Stocks . . . . . . .199 A. Mutant stocks ......... 199 B. Marker stocks 202 C. Isogenic stocks . . . . . . . . . 203 III. Sources of Stocks 205 IV. Maintenance of Special Genetic Stocks ...... 206 A. General .......... 206 B. Particular types of mutants ....... 207 C. Chromosome anomalies ....... 224 D. Preparation and maintenance of isogenic strains . . . 226 References 231 8. Inbreeding and Selection marjorie dinsley I. Inbreeding 235 A. Reduction of hetero2ygosity . . . . . . .236 B. Inbreeding depression ........ 239 C. Maintaining an inbred strain ...... 240 D. Maintaining a non-inbred strain ...... 243 E. Choice of breeding method ....... 246 F. Production of inbred animals in large numbers . . . 247 II. Selection ........... 248 A. Response to selection ........ 249 B. Selection for qualitative, quantitative and threshold characters . 253 C. Methods of selection ........ 255 D. Selection for fertility ........ 256 References 257 9. Matching the Animal with the Experiment annie м. brown I. The Animal to Hand and Advances in Biology during the Past 200 Years ........... 261 A. As a substitute for man in toxicology ..... 261 B. In the problems of adequate nutrition ..... 263 C. At the beginning of microbiology and immunology . . . 263 D. In endocrinology ......... 264 E. As a tool for the psychologist ...... 264 F. In medicine and surgery 265 II. Animal Characteristics and Research Projects .... 265 A. Animals with characteristics resembling those in man . . 265 B. Animals with unique features of anatomy and physiology . 267 C. Animals with special features of metabolism .... 269 D. Animals with ability to learn . . . . . .271 E. Animals with useful breeding habits and high productivity . 271 F. Animals used for their inbred state ..... 272 G. Animals with uses where documentation counts . . .273 H. Animals used for their disease susceptibility .... 275 I. Unusual species and their uses ...... 275