Mammalian chimaeras / Anne McLaren.

  • McLaren, Anne.
Date:
[1976]
Catalogue details

Licence: Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)

Credit: Mammalian chimaeras / Anne McLaren. Source: Wellcome Collection.

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    Spontaneous chimaeras 121 Fig. 40. Skin chimaerism in an XXjXY boy of mixed Negro-Amerindian-Caucasian ancestry. The darker skin, XX in chromosome constitution, grew more slowly in culture than the paler XY skin, and constituted only about 10 % of the total body surface. From Zuelzer et al. (1964). Mrs T.R. in being fertile and having two XX cell lines; it showed yellow and black stripes, since the two lines differed with respect to a coat colour marker, and analysis of the progeny showed that two populations of germ cells were also present, differing at four loci. Male tortoiseshell cats show a bewildering range of sex chromosome abnormalities (for review, see Jones, 1969); some at least are believed to represent primary chimaerism (e.g. Chu, Thuline & Norby, 1964). It is often possible to show, by comparison of the blood groups of the chimaeric individual and its parents, that either the father or the mother or both have made two genetic contributions to the chimaera, one to each cell